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Small Scale Optimization of an Active Formulation Roller Compaction Process Using a True Placebo Des

Released By Thermo Fisher Scientific Pharma Services

The purpose of this study was to evaluate the use of a true placebo DoE to create a platform process in which to define a viable active formulation process on a roller compactor. The use of placebo DoE was effective in creating a platform process for active feasibility trials and scale-up using minimal API.

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